Production of anti‐SARS‐CoV‐2 hyperimmune globulin from convalescent plasma
نویسندگان
چکیده
منابع مشابه
A randomized trial of hyperimmune globulin to prevent congenital cytomegalovirus.
BACKGROUND Congenital infection with human cytomegalovirus (CMV) is a major cause of morbidity and mortality. In an uncontrolled study published in 2005, administration of CMV-specific hyperimmune globulin to pregnant women with primary CMV infection significantly reduced the rate of intrauterine transmission, from 40% to 16%. METHODS We evaluated the efficacy of hyperimmune globulin in a pha...
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n engl j med 374;25 nejm.org June 23, 2016 2498 cizumab according to two definitions of refractoriness.2,3 Regardless of the definition, a lower percentage of patients in the caplacizumab group than in the placebo group had disease that was refractory to treatment, which suggests that caplacizumab might prevent refractory TTP and its associated worse outcomes.1 To clarify, Table 3 of our articl...
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Determinations of the rates of antibody synthesis during first, second, and hyperimmune responses to bovine gamma globulin using S(35)-labelle aminod acids indicate the following: 1. In all three responses the rate of antibody synthesis increases while antigen is circulating and then begins to decline rapidly after elimination of detectable circulating antigen. 2. The initial rates of decline o...
متن کاملIn vitro and in vivo activity of hyperimmune globulin preparations against multiresistant nosocomial pathogens
PURPOSE We compared different immunoglobulin preparations containing IgG (Intraglobin/Intratect) or a mixture of IgG, IgA, and IgM (Pentaglobin) to assess the opsonic and protective efficacy of human immunoglobulin preparations against multiresistent nosocomial pathogens. MATERIALS AND METHODS Clinical isolates of E. coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Enterococcus faecalis, ...
متن کاملThe Effectiveness of Convalescent Plasma and Hyperimmune Immunoglobulin for the Treatment of Severe Acute Respiratory Infections of Viral Etiology: A Systematic Review and Exploratory Meta-analysis
BACKGROUND Administration of convalescent plasma, serum, or hyperimmune immunoglobulin may be of clinical benefit for treatment of severe acute respiratory infections (SARIs) of viral etiology. We conducted a systematic review and exploratory meta-analysis to assess the overall evidence. METHODS Healthcare databases and sources of grey literature were searched in July 2013. All records were s...
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ژورنال
عنوان ژورنال: Transfusion
سال: 2021
ISSN: 0041-1132,1537-2995
DOI: 10.1111/trf.16378